2 edition of Ibutilide as a firstline antiarrhythmic drug in a porcine model of out-of-hospital cardiac arrest. found in the catalog.
Ibutilide as a firstline antiarrhythmic drug in a porcine model of out-of-hospital cardiac arrest.
Cameron Reid Smith
Results and Conclusions. Ibutilide increased DFT (161.1 +/- 33.3 J vs. 200 +/- 54.8 J, p = 0.044). Ibutilide did not significantly change any other variable measured. The ITV did not significantly change any variable measured. Ibutilide appears inactive in the pig, while the ITV may not function properly when used with automatic ventilators.Objectives. Class III antiarrhythmics have been demonstrated to lower defibrillation threshold (DFT). The impedance threshold valve (ITV) has been demonstrated to improve hemodynamics during cardiopulmonary resuscitation (CPR). We hypothesize that administration of the class III antiarrhythmic drug ibutilide, and use of the ITV during CPR after induction of ventricular fibrillation (VF) will lead to greater short-term survival vs. control.Methods. VF was induced in 30--35 kg pigs and left untreated for 4 minutes. CPR was performed for 8 minutes using automatic ventilation. 0.005 mg/kg IV ibutilide was administered during CPR. Electrophysiologic and hemodynamic variables were measured at baseline, during CPR, and post-resuscitation.
|The Physical Object|
|Number of Pages||122|
Sans Queue Ni Tete
Industrial estate and industrial zone in East Java.
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Aboriginal water rights in Canada
geographical and statistical view of Massachusetts proper.
art of block building.
Phase II of the Presidents new economic program.
Cotton to 1996
The social glass, or, Victims of the bottle
Direct loading with the Koehring harvester